"We got Carlos [Quentin], we have [Alex] Rios, PK [Paul Konerko] and JD [Jermaine Dye], almost in the same way," Guillen said.
"I think if two out of those four guys get hot, I think it's going be interesting. Because if we play the way we play right now with those guys hot, that means we can do some damage."
Quentin, who missed almost two months with plantar fasciitis until returning at the end of July, is hitting .238 with eight home runs and 19 RBIs since his return. Konerko is batting .280 with 26 homers and 82 RBIs, Dye is at .253 with 25 home runs and 72 RBIs and Rios is at .243 with 15 homers and 65 RBIs.
The White Sox trail the Tigers by six games in the AL Central with 18 games to play.
"Every day is going to be interesting," Guillen said. "It's about us winning. It's not about what Detroit does. If we continue to win, that's our goal. To make sure that when we face them, we're close enough to compete.
"Just make sure we stay in it, stay close to it. Then when we face them, hopefully we'll get hot. It's something I don't think it's impossible. When those guys get hot, they can carry a ballclub."
The White Sox end their last homestand of the season with three games against the Tigers from Sept. 25-27, before ending the regular season a week later with three games at Detroit.
But they can read a calendar the same as anyone else and recognize that they can't sit around and wait for their bats to suddenly get hot.
"It's hard, especially since Detroit is not going to lose that many games because that pitching staff is throwing the ball well," Guillen said. "We cannot worry about Detroit. We have to win as many games as we can."
The White Sox have won seven of their past 11 games, but have gained only one game in the standings.
CWS: RHP Freddy Garcia (1-2, 4.40 ERA)
Working at his customary slow pace on the mound, Garcia lasted six innings, scattering two runs on five hits with five strikeouts, earning a no-decision in Wednesday's 4-3 victory against the A's. Garcia now has made five starts since rejoining the White Sox rotation on Aug. 18, and his consistency appears to be making him a prime candidate for Chicago's fifth starter role next season. Wednesday's game marked Garcia's fourth consecutive quality start. That is his longest stretch of quality starts since recording six in a row from April 22 - May 20, 2006. Lifetime against the Mariners, Garcia is 2-3 with a 6.28 ERA in six starts.
SEA: RHP Ian Snell (6-10, 5.28 ERA)
A rough outing in his start against the Angels led to Snell seeing his four-game winning streak come to an end. He was one victory from matching his career-best streak. Periods of losing touch with the strike zone proved costly for the right-hander, who walked two batters in the first and sixth innings -- the two frames he surrendered runs. Snell wobbled early, which has been his pattern this season. Of the 125 hits he has allowed, 72 of them have occurred in his first 30 pitches of his starts, including 10 of the 13 home runs he's surrendered. This will be his first start against the White Sox.
Jake Peavy threw an encouraging bullpen session on Sunday and said he felt ready to make his White Sox debut. "I would certainly think so. I threw 65 good pitches today, and that's after I got loose," he said. "I'm close to being ready to go into a game. I'll just wait and see what decision the team makes." The Sox, however, are expected to have him throw one more bullpen session before he likely starts next weekend against Kansas City. Peavy was hit on the right elbow by a line drive three weeks ago. ... The White Sox have lost seven of their past 10 on the road. ... Left-hander Mark Buehrle is now two innings shy of reaching 200 innings pitched for his ninth consecutive season, already the longest streak in baseball. ... Sunday's loss marked the first time the White Sox lost a series to the Angels in Anaheim since 2004. ... Scott Podsednik went 0-for-5 on Sunday to snap a season-high 11-game hitting streak.
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Official game notes
Wednesday: White Sox (TBD) at Mariners (Ryan Rowland-Smith, 3-3, 3.88), 9:10 p.m. CT
Thursday: White Sox (TBD) at Mariners (Brandon Morrow, 1-4, 5.29), 5:40 p.m. CT
Friday: White Sox (John Danks, 12-9, 3.71) vs. Royals (Luke Hochevar, 6-10, 6.23), 7:11 p.m. CT