Sale will again be matched against Royals ace James Shields. The White Sox left-hander was in that position on Opening Day at U.S. Cellular Field and came out on top as Chicago prevailed, 1-0.
"I want to build on that," Sale said.
Manager Robin Ventura said Hector Santiago will get the ball for the opener of the Yankees series on Tuesday and the White Sox will wait and see if Peavy is healthy enough to start on Wednesday.
Sale relishes the opportunity to match up against another club's No. 1 starter.
"It's always fun getting their best guy," Sale said. "It's what you want. It's not going to be easy, but it's a challenge and we look forward to challenges. That's the nature of the game."
Sale is 3-2 with a 3.83 ERA, while Shields is 2-2 with a 3.00 ERA.
Robert Falkoff is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.