It was the White Sox who jumped out to a quick 3-0 first-inning lead against Homer Bailey with Dunn's mammoth three-run homer off the center-field batters' eye. Cincinnati evened the score in the bottom of the first against left-hander John Danks as Heisey hit an RBI single and Todd Frazier hit a two-run single.
After the Reds added two more runs against Danks in the second inning, Chicago countered with two third-inning runs against Bailey, including Gordon Beckham's leadoff homer to left field.
The big damage came during a five-run bottom of the fourth in which 10 men batted. Heisey banged a three-run homer to left field on a 2-1 pitch and Jay Bruce made it back-to-back shots by hitting a 1-1 pitch that barely cleared the fence in right field.
"I felt like I was ahead in the count, but I just wasn't able to make that pitch," Danks said. "I don't think it was so much stuff as it was that I just wasn't ever able to make a good enough pitch to put them away. Give them some credit, they hit some tough pitches and fouled off some tough pitches and got it to where I would make a mistake and they'd hit it."
Danks left after allowing 10 earned runs and 11 hits, with two walks and no strikeouts, over 3 1/3 innings
"It would have been nice to have a good one today. I had anything but," Danks said. "I've got to keep plugging along."
Bailey gave up five runs (four earned) on nine hits, with one walk and five striketouts, over 4 1/3 innings.
"I was feeling good. That's the most important thing," Bailey said. "Probably from the stretch, my slider and curveball wasn't quite where I wanted it. That could be the thin air, it could be me and it could be a bunch of things."
The Reds' Derrick Robinson had three hits and scored three times out of the leadoff spot.
White Sox left fielder Dayan Viciedo, who tripled in a run during the third, left the game in the middle of the fourth inning because of a cramp in his right quadriceps, but he is expected to be back in action Wednesday.
Up next: Right-hander Gavin Floyd gets the ball for a 3:05 p.m. CT first pitch against the D-backs on Wednesday. In two outings this spring, Floyd has tossed 8 2/3 innings, allowing five runs on 11 hits -- a number he's looking to limit. After Floyd, Hector Santiago and Nate Jones are penciled in to come out of the White Sox bullpen. The game can be seen on a free whitesox.com video webcast.