Paul Konerko, Gordon Beckham and Dayan Viciedo were all absent from Chicago's lineup. Orlando Hudson started at second base and Jordan Danks was slotted in left field. Eduardo Escobar's start at third base shifted Kevin Youkilis over to first.
"It's for the long haul," Ventura said before the White Sox 12:10 p.m. CT getaway game with Minnesota. "Guys got to play. This is a good time -- when you get these day games like this -- to get these guys in there who have been on the bench a little bit."
Youkilis -- who had two hits in his first two games with his new club -- has experience at first base, giving the Chicago manager more flexibility with his lineup.
"I talked to him about it when he first got here," Ventura said. "He's played a lot of it. So it's not the same thing, like we did with Orlando, trying to make him a third baseman. He's fine with it. It's just one of those things we'll end up doing."
Hudson's start was his first since Youkilis was acquired from Boston. Youkilis' flexibility allowed Ventura to give Konerko a day off while still putting Hudson at his natural position.
"We'll use him in different situations, either at second or at third," Ventura said. "I think now's a good time to play both of them on the same day, to get him over there, where he's comfortable."