Adam Dunn, Alex Rios and Brent Morel swung the pink bats in the starting lineup, while A.J. Pierzynski and Alejandro De Aza used them off the bench.
"It's been going on for a couple of years," said Rios of the pink bats. "I always use them just to support the cause."
The pink bats produced four hits for the White Sox, but it was Major League Baseball's unwavering support of true unsung heroes that meant the most on this day.
"What Major League Baseball does as far as honoring this day and breast cancer awareness, it's a big day and we like to show support," White Sox manager Robin Ventura said. "Guys realize what their moms have done and what their wives do, as far as raising the kids while you're gone. It's an important day for us."