Vazquez (7-5) will take the mound for the White Sox hoping to avoid a Cubs sweep and end a five-game North Siders winning streak in the crosstown series. He'll be opposed by Ryan Dempster, who is 8-0 at Wrigley Field.
The Cubs have the best team batting average in the Majors. The White Sox boast more home runs than any team in the AL. If the wind is blowing out again, another scoring barrage could result.
Still, it'll be a shock if Vazquez doesn't fare better than Jose Contreras did on Saturday (eight runs allowed in 3 1/3 innings). Given his recent outings, Vazquez could use a strong performance, not only to quiet Cubs fans, but also to get himself back on track.
Vazquez has allowed five runs in consecutive starts for the first time since May of last year. He gave up five runs on 10 hits in a loss to Detroit on June 11. Vazquez then turned in a five-run, five-hit line Tuesday while the Sox demolished the Pirates, 16-5.
"I've not been ahead in the count, as I should," he said. "I just need to be more aggressive, get after hitters a little bit more. It's part of pitching. It's all about getting ahead in the count and not being behind."
CWS: RHP Javier Vazquez (7-5, 4.13 ERA)
Vazquez struggled in his third consecutive outing Tuesday night, but the performance was good enough to pick up the win, and manager Ozzie Guillen was pleased to see his ace get through six innings on a bad night. Vazquez has allowed 14 runs in his last three starts but is 2-1 in that stretch, having gotten plenty of help from his offense. Vazquez has started three games against the Cubs but has never factored in the decision. He owns a 4.95 ERA against the crosstown rivals but has struck out 23 against just two walks.
CHC: RHP Ryan Dempster (8-2, 2.76 ERA)
Dempster will be happy to be home. He did not get a decision in his last start against Tampa Bay and remains winless on the road. However, he's 8-0 with a 3.13 ERA at Wrigley Field. Against the Rays, he gave up one run on six hits over five innings and had to be pulled when his pitch count got high. He fanned six, but threw 107 pitches in the five innings.
Catcher A.J. Pierzynski extended his Major League-leading hitting streak to 15 games with a fifth-inning single Saturday. He is one game shy of the personal career high he set from May 16-June 14, 2002. ... Orlando Cabrera is .321 (9-for-28) lifetime against Dempster. ... White Sox manager Ozzie Guillen said he would rather face Jim Edmonds than Alfonso Soriano, and that Edmonds is "not gonna scare me" after Edmonds' two-homer game Saturday. Well, Edmonds likely won't be afraid to face Vazquez. He is 8-for-17 with two dingers in his career off him. ... Brad Eldred hit his league-leading 25th home run of the season in Triple-A Charlotte's 8-2 win over Lehigh Valley on Friday night.
111-93 overall, 7-4 in 2008
2008 Interleague Schedule
May 16 at Giants: Won, 2-0
May 17 at Giants: Won, 3-1
May 18 at Giants: Won, 13-9
June 13 vs. Rockies: Won, 5-4
June 14 vs. Rockies: Lost, 2-0
June 15 vs. Rockies: Lost, 5-3
June 17 vs. Pirates: Won, 16-5
June 18 vs. Pirates: Won, 8-2
June 19 vs. Pirates: Won, 13-8
June 20 at Cubs: Lost, 4-3
June 21 at Cubs: Lost, 11-7
June 22 at Cubs
June 24 at Dodgers
June 25 at Dodgers
June 26 at Dodgers
June 27 vs. Cubs
June 28 vs. Cubs
June 29 vs. Cubs
All-time record vs. Cubs:
On the Internet
Official game notes
Tuesday: White Sox (Mark Buehrle, 4-6, 4.28) at Dodgers (Derek Lowe, 5-6, 3.90), 9:10 p.m. CT
Wednesday: White Sox (Gavin Floyd, 8-3, 3.19) at Dodgers (Eric Stults, 1-0, 1.50), 9:10 p.m. CT